WR3 should be in question unless you just hand it to the rookie in Pickens. He has huge upside but limited experience. I do believe we'll see more of Claypool in the slot this year with Pickens on the outside when he locks down a key role.
I think QB1 is set, but they'll give a perceived competition. From a coaching standpoint, yes, not really a battle.
Most of us could already get, as you said, 48-50, guys on the roster. Even the guys who emerge, how many ever make the team? They released Roche, who showed some potential at a position that desperately needed depth to keep IIRC an extra ILB.