James Harrison failed to practice for the third consecutive day on Friday and will not be available on Sunday in Indianapolis.
Several years ago this may have been huge news, but with Harrison relegated to a back up role it shouldn't change much of anything as the Steelers get ready for the Colts.
Mike Mitchell was not on the Steelers injury report today so it's safe to say he should start on Sunday after dealing with an achilles injury.
Vance McDonald, Stephon Tuitt, and Marcus Gilbert will all return to the starting lineup after they've missed time with injuries.
Everyone else is healthy as the Steelers start the second half of the season.
